Effects of a 4-Week Moderate-Intensity Swimming Exercise Increase Serotonin Levels in Mice (Mus musculus)

Serotonin is a neurotransmitter that important in maintaining the integrity of body functions, regulating mood, emotion, sleep, appetite, and memory function. However, changes serotonin its receptors are associated with development anxiety, depression, psychiatric disorders, such as schizophrenia. Exercise suggested treatment for several disorders. The study aims to prove effect moderate-intensity swimming exercise 4 weeks on increasing levels male mice (Mus musculus). was true experiment research design from randomized control group posttest-only designs using 20 musculus), eight age, weighing 30-35 grams randomly divided into two groups, CTL (n = 10, group), MIE exercise). Moderate-intensity carried out frequency 3 times/a weeks. Measurement Enzyme-Linked Immunosorbent Assay (ELISA) method. Data analyzed Independent Samples T-Test significant level (p ? 0.01). results showed difference between (100.61?20.08 vs. 57.06?5.13 ng/mL 0.001)). Based concluded increases